Description

4-(3-Amino-6-((1S,3S,4S)-3-Fluoro-4-Hydroxycyclohexyl)Pyrazin-2-Yl)-2-Fluoro Benzoic Acid is a sophisticated, high-purity pharmaceutical intermediate designed for advanced drug discovery and development. This compound is critical for medicinal chemists working on targeted therapies, particularly in oncology and other disease areas requiring precise molecular modulation. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the research and development of potential anti-cancer agents due to its specific fluorinated and functionalized structure.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Employed in the production of compounds for pharmacological profiling, toxicology studies, and early-stage formulation development.
• Custom Synthesis: A starting material for the custom synthesis of complex molecules and reference standards for analytical purposes.
• Biochemical Research: Used as a tool compound to study specific biological pathways and protein-ligand interactions.

Basic Information

Product Name	4-(3-Amino-6-((1S,3S,4S)-3-Fluoro-4-Hydroxycyclohexyl)Pyrazin-2-Yl)-2-Fluoro Benzoic Acid
CAS No.	1715032-88-4
Molecular Formula	C₁₇H₁₈F₂N₄O₃
Molecular Weight	364.35 g/mol
Synonyms	4-(3-Amino-6-((1S,3S,4S)-3-Fluoro-4-Hydroxycyclohexyl)Pyrazin-2-Yl)-2-Fluorobenzoic Acid; (1S,3S,4S)-4-[3-Amino-6-(4-Carboxy-3-fluorophenyl)pyrazin-2-yl]-2-fluorocyclohexan-1-ol; 2-Fluoro-4-[3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl]benzoic Acid; 1715032-88-4; UNII-6K4W2J8Y1U; 6K4W2J8Y1U; Benzoic acid, 2-fluoro-4-[3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]-2-pyrazinyl]-; AKOS040759583; FT-0773295.
EINECS	Contact for details

Quality Control

Our production of 4-(3-Amino-6-((1S,3S,4S)-3-Fluoro-4-Hydroxycyclohexyl)Pyrazin-2-Yl)-2-Fluoro Benzoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR for structural confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.