Description

(3-(1-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Ethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a protected piperazine moiety, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its dual functionality, serving as a key intermediate in the synthesis of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing new active ingredients, such as kinase inhibitors and other biologically relevant heterocycles. The CAS number for this compound is 1704096-32-1.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted drug candidates, especially for oncology and central nervous system (CNS) therapies.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl scaffolds prevalent in medicinal chemistry.
• Kinase Inhibitor Development: Used in the research and production of small molecule kinase inhibitors due to its specific structural motif.
• Agrochemical Synthesis: Employed in creating advanced active ingredients for crop protection with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Acts as a monomer or functionalization agent in the development of novel organic electronic materials and polymers.

Basic Information

Product Name	(3-(1-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Ethyl)Phenyl)Boronic Acid
CAS No.	1704096-32-1
Molecular Formula	C₁₇H₂₇BN₂O₄
Molecular Weight	334.22 g/mol
Synonyms	[3-[1-[4-[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl]ethyl]phenyl]boronic acid; Boc-Piperazine Boronic Acid Derivative; 3-(1-(4-(Boc)Piperazin-1-yl)ethyl)benzeneboronic acid; N-Boc-4-(1-(3-boronophenyl)ethyl)piperazine; 1-Boc-4-(1-(3-boronobenzyl))piperazine; tert-Butyl 4-(1-(3-boronophenethyl))piperazine-1-carboxylate; 1704096-32-1
EINECS	Contact for details

Quality Control

Our (3-(1-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Ethyl)Phenyl)Boronic Acid is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research and cGMP applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.