Description

4-(2-Bromo-4-(Difluoromethyl)Phenyl)Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic morpholine structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and manufacturing organizations in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the difluoromethyl and bromo substituents for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential building block for specialty polymers and advanced organic electronic materials due to its aromatic and heterocyclic components.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4-(2-Bromo-4-(Difluoromethyl)Phenyl)Morpholine
CAS No.	1704080-67-0
Molecular Formula	C11H12BrF2NO
Molecular Weight	292.12 g/mol
Synonyms	4-(2-Bromo-4-(difluoromethyl)phenyl)morpholine; Morpholine, 4-[2-bromo-4-(difluoromethyl)phenyl]-; 2-Bromo-4-(difluoromethyl)phenylmorpholine; 4-(2-Bromo-4-difluoromethylphenyl)morpholine; 1704080-67-0; Bromo-difluoromethylphenyl morpholine
EINECS	Contact for details

Quality Control

Our production of 4-(2-Bromo-4-(Difluoromethyl)Phenyl)Morpholine adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment. Our quality system is designed to support customer requirements for both research and cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.