Description

(3-(3-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Propoxy)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a protected piperazine moiety. This compound is a critical high-purity building block in modern organic synthesis, valued for its dual functionality in cross-coupling reactions and as a key intermediate for complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to medicinal chemistry.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors, leveraging the piperazine scaffold for targeted binding.
• Chemical Biology & PROTACs: Employed as a linker or warhead component in the design of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
• Advanced Material Synthesis: Acts as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP and non-GMP production of bespoke organic compounds.

Basic Information

Product Name	(3-(3-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Propoxy)Phenyl)Boronic Acid
CAS No.	1704063-56-8
Molecular Formula	C18H29BN2O5
Molecular Weight	364.25 g/mol
Synonyms	3-[3-[4-[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl]propoxy]benzeneboronic Acid; Boc-Piperazine Propoxyphenyl Boronic Acid; N-Boc-4-(3-(3-Boronophenoxy)propyl)piperazine; (3-(3-(4-(Boc)Piperazin-1-yl)propoxy)phenyl)boronic acid; 1-Boc-4-[3-(3-boronophenoxy)propyl]piperazine; 3-(3-(4-(tert-Butoxycarbonyl)piperazin-1-yl)propoxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our (3-(3-(4-(tert-Butoxycarbonyl)Piperazin-1-Yl)Propoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.