Description

Methyl 5-Chloro-6-(Trifluoromethyl)Pyrazine-2-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a reactive pyrazine core with chlorine and trifluoromethyl substituents, enabling precise molecular modifications and the introduction of desirable physicochemical properties. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a crucial building block for creating next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Used in the synthesis of advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 5-Chloro-6-(Trifluoromethyl)Pyrazine-2-Carboxylate
CAS No.	1688685-61-1
Molecular Formula	C7H4ClF3N2O2
Molecular Weight	240.57 g/mol
Synonyms	5-Chloro-6-(trifluoromethyl)pyrazine-2-carboxylic acid methyl ester; Methyl 5-chloro-6-(trifluoromethyl)pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 5-chloro-6-(trifluoromethyl)-, methyl ester; 5-Chloro-6-trifluoromethyl-pyrazine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-6-(Trifluoromethyl)Pyrazine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.