Description

(Des-Gly2)-Exenatide is a synthetic analog of the glucagon-like peptide-1 (GLP-1) receptor agonist exenatide, specifically designed for research and pharmaceutical development. This compound is of significant interest for its potential role in metabolic disorder research and the development of next-generation therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology and diabetes. The product is supplied as a high-purity peptide to ensure reliable and reproducible experimental results.

Application

• Pharmaceutical Reference Standard: Serves as a critical benchmark for the quality control and analytical method development of GLP-1 based therapeutics.
• Metabolic Research: Used in preclinical studies to investigate mechanisms of glucose homeostasis, insulin secretion, and appetite regulation.
• Drug Discovery & Development: Acts as a key intermediate or active pharmaceutical ingredient (API) in the synthesis and formulation of novel anti-diabetic drugs.
• Biochemical Assays: Employed in receptor binding studies, potency assays, and other in vitro tests to evaluate biological activity.
• Structure-Activity Relationship (SAR) Studies: Utilized to understand the impact of specific amino acid modifications on peptide stability and efficacy.

Basic Information

Product Name	(Des-Gly2)-Exenatide
CAS No.	1678416-78-8
Molecular Formula	C184H282N50O60S
Molecular Weight	4187.6 g/mol
Synonyms	Exendin-4 (2-39); Exenatide (2-39); (Des-Gly2)-Exendin-4; LY2148568 (2-39); AC2993 (2-39); GLP-1 Receptor Agonist Analog; Synthetic Exendin-4 Fragment
EINECS	Contact for details

Quality Control

Our (Des-Gly2)-Exenatide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the rigorous demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (MS)	Conforms
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.