Description

Lipoamido-Peg2-Alcohol CAS NO 1674386-82-3 is a specialized bifunctional PEG derivative featuring a lipoamide moiety and a terminal hydroxyl group. This compound is a critical building block in bioconjugation and pharmaceutical development, enabling the precise modification of biomolecules to enhance solubility, stability, and targeting. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, proteomics, and advanced drug delivery systems.

Application

• Bioconjugation Reagent: Used for site-specific modification of peptides, proteins, and antibodies to attach therapeutic payloads or imaging agents.
• Linker for Drug Delivery: Serves as a functional spacer in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Surface Functionalization: Employed to modify nanoparticles, liposomes, and other drug carrier surfaces to improve biocompatibility and active targeting.
• Proteomics Research: Acts as a tool compound for labeling and studying protein interactions and dynamics.
• Polymer Chemistry: Functions as a monomer or cross-linking agent in the synthesis of functionalized, biodegradable polymers for medical applications.
• Diagnostic Assay Development: Utilized in the preparation of enzyme conjugates and other reagents for immunoassays and biosensors.

Basic Information

Product Name	Lipoamido-Peg2-Alcohol
CAS No.	1674386-82-3
Molecular Formula	C15H30N2O6S2
Molecular Weight	398.54 g/mol
Synonyms	6,8-Dimercaptooctanoic acid-PEG2-alcohol; α-Lipoic acid-PEG2-OH; 5-{1,2-Dithiolan-3-yl}-N-(2-hydroxyethoxy)ethylpentanamide; Thioctic acid-PEG2-alcohol; Lipoamide-PEG2-alcohol; 1,2-Dithiolane-3-pentanamide, N-(2-(2-hydroxyethoxy)ethyl)-; Lipoic acid amide PEG2 alcohol
EINECS	Contact for details

Quality Control

Our Lipoamido-Peg2-Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.