Description

8-Bromo-Imidazo[1,2-A]Pyrazine-6-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel pharmaceutical candidates, particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic areas. It is primarily utilized by research institutions, CROs/CDMOs, and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic scaffolds in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Kinase Inhibitor Development: Serves as a core structural element in the synthesis of potential kinase inhibitors due to the imidazopyrazine moiety.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and pesticides.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and ligands for catalysis.
• Custom Synthesis & Scale-Up: Supplied to contract research and manufacturing organizations for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	8-Bromo-Imidazo[1,2-A]Pyrazine-6-Carboxylic Acid Methyl Ester
CAS No.	1660116-54-0
Molecular Formula	C8H6BrN3O2
Molecular Weight	256.06 g/mol
Synonyms	Methyl 8-bromoimidazo[1,2-a]pyrazine-6-carboxylate; 8-Bromoimidazo[1,2-a]pyrazine-6-carboxylic acid methyl ester; Imidazo[1,2-a]pyrazine-6-carboxylic acid, 8-bromo-, methyl ester; 1660116-54-0; Methyl 8-bromo-imidazo[1,2-a]pyrazine-6-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Bromo-Imidazo[1,2-A]Pyrazine-6-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated and non-regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.