Description

4-tert-Butyloxycarbonyl-1-Nitropiperazine is a specialized piperazine derivative featuring both a Boc (tert-butoxycarbonyl) protecting group and a nitro functional group. This compound is a crucial pharmaceutical intermediate and building block in organic synthesis, valued for its role in constructing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing piperazine cores.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, leveraging the nitro group for further functionalization.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of certain herbicides and fungicides.
• Peptide Mimetics & Modifications: The Boc-protected amine is instrumental in creating peptide analogs and modifying peptide structures.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and other synthetic transformations.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-tert-Butyloxycarbonyl-1-Nitropiperazine
CAS No.	1657030-78-8
Molecular Formula	C9H17N3O4
Molecular Weight	231.25 g/mol
Synonyms	1-Nitro-4-(tert-butoxycarbonyl)piperazine; tert-Butyl 4-nitropiperazine-1-carboxylate; 4-Nitro-1-piperazinecarboxylic acid tert-butyl ester; 1-Boc-4-nitropiperazine; Boc-4-nitropiperazine; 4-Nitro-1-Boc-piperazine; 1-(tert-Butoxycarbonyl)-4-nitropiperazine; Piperazine, 1-nitro-4-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our 4-tert-Butyloxycarbonyl-1-Nitropiperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent quality suitable for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.