Description

2-Chloro-4-(6-Methylpyrazin-2-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrazine-aniline hybrid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers developing next-generation drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Academic & Contract Research: Essential for synthetic chemistry studies and as a reference standard in analytical laboratories.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Chloro-4-(6-Methylpyrazin-2-Yl)Aniline
CAS No.	1648864-30-5
Molecular Formula	C11H10ClN3
Molecular Weight	219.67 g/mol
Synonyms	2-Chloro-4-(6-methylpyrazin-2-yl)benzenamine; 4-Amino-3-chloro-1-(6-methylpyrazin-2-yl)benzene; 2-Chloro-4-(6-methyl-2-pyrazinyl)aniline; 2-Chloro-4-(6-methylpyrazin-2-yl)phenylamine; Benzenamine, 2-chloro-4-(6-methyl-2-pyrazinyl)-; 1648864-30-5; 2-(2-Chloro-4-aminophenyl)-6-methylpyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(6-Methylpyrazin-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.