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Azido-Peg10-Acid CAS NO 1644163-57-4


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CAS No.:1644163-57-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Azido-Peg10-Acid is a heterobifunctional polyethylene glycol (PEG) linker featuring a reactive azide group at one terminus and a carboxylic acid group at the other. This compound is essential for creating stable, biocompatible conjugates in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics industries for developing antibody-drug conjugates (ADCs), peptide modifications, and functionalized nanoparticles.

Application

  • Bioconjugation reagent for linking biomolecules (e.g., peptides, proteins, antibodies) via click chemistry.
  • Critical component in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted therapeutics.
  • Surface functionalization and modification of nanoparticles, quantum dots, and other nanomaterials.
  • Preparation of cross-linked hydrogels and polymeric materials for drug delivery systems.
  • Tool compound for proteomics research and the study of protein-protein interactions.
  • Intermediate in the synthesis of complex PEGylated prodrugs and diagnostic agents.
  • Linker for immobilizing biomolecules onto biosensor chips and solid supports.

Basic Information

Product Name Azido-Peg10-Acid
CAS No. 1644163-57-4
Molecular Formula C24H47N3O12
Molecular Weight 569.65 g/mol
Synonyms Azido-PEG10-acid; 3-Azidopropyl-PEG10-acid; 3-Azidopropyl-PEG10-COOH; Azido-PEG10-COOH; N3-PEG10-Acid; 3-Azidopropyl-(ethylene glycol)10-acetic acid; Azido-PEG10-propionic acid; Azido-PEG10-COOH
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Quality Control

Our Azido-Peg10-Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional group integrity. We adhere to relevant industry standards for research-grade and GMP-starting materials, ensuring suitability for critical applications in drug discovery and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Functional Group Assay (NMR/Titration) ≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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