Description

Maresin 2 is a specialized pro-resolving lipid mediator (SPM) derived from the docosahexaenoic acid (DHA) pathway, identified by CAS NO 1639809-46-3. This compound plays a critical role in actively promoting the resolution of inflammation and tissue repair, offering a targeted mechanism beyond simple anti-inflammatory action. It is an essential research biochemical for pharmaceutical R&D, biotechnology, and academic institutions focused on inflammation biology, immunology, and the development of novel therapeutic agents for chronic inflammatory diseases.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the molecular mechanisms of inflammation resolution, macrophage function, and tissue regeneration.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore model for developing new classes of resolution pharmacology-based therapeutics.
• In Vitro & In Vivo Studies: Applied in cell culture assays and animal models to study its effects on specific inflammatory pathways and disease states.
• Analytical Standard: Employed as a high-purity standard for the qualitative and quantitative analysis (e.g., via LC-MS/MS) of maresin pathways in biological samples.
• Biochemical Reagent: Utilized in enzymatic studies and signal transduction research related to specialized pro-resolving mediator receptors and pathways.

Basic Information

Product Name	Maresin 2
CAS No.	1639809-46-3
Molecular Formula	C22H32O4
Molecular Weight	360.49 g/mol
Synonyms	7R,14S-Dihydroxy-4Z,8E,10Z,12E,16Z,19Z-docosahexaenoic acid; MaR2; Maresin-2; 7R,14S-diHDHA; (4Z,7R,8E,10Z,12E,14S,16Z,19Z)-7,14-Dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid; Pro-resolving Lipid Mediator MaR2; Docosanoid MaR2
EINECS	Contact for details

Quality Control

Our Maresin 2 is produced under stringent conditions to ensure high chemical purity and biological activity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous internal quality standards suitable for research applications, with specifications tailored to meet the demands of analytical and bioactivity studies.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere. Once opened, the product should be handled under an inert gas (e.g., argon or nitrogen) to prevent oxidation, aliquoted if necessary, and returned promptly to the recommended freezer conditions. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.