Description

(8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Piperazine-1,4-Dione is a high-purity, specialized heterocyclic compound with the CAS registry number 1638744-87-2. This advanced pharmaceutical intermediate is critical for research and development in modern drug discovery programs, particularly for its potential role in constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new pharmacophores.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design and synthesis of peptidomimetics, which mimic the structure and function of peptides.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing custom APIs for clinical trials.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Piperazine-1,4-Dione
CAS No.	1638744-87-2
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(8aR)-8a-Methylhexahydro-1H,3H-pyrrolo[1,2-a]piperazine-1,4-dione; (8aR)-8a-Methyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione; 8a-Methyl-1,2,3,6,7,8-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; (R)-8a-Methyloctahydropyrrolo[1,2-a]piperazine-1,4-dione; Pyrrolopiperazinedione derivative; 1638744-87-2; SCHEMBL21824027
EINECS	Contact for details

Quality Control

Our (8Ar)-8A-Methyl-Octahydropyrrolo[1,2-A]Piperazine-1,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.