Description

Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide, 4,5,6,7-Tetrahydro-2-(4-Phenoxyphenyl)-7-(4-Piperidinyl)-, (7S)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure, designed for the synthesis of novel therapeutic agents. This compound matters as a critical building block in medicinal chemistry, enabling the development of targeted small-molecule drugs with potential applications in oncology and central nervous system disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this precisely defined chiral intermediate to accelerate their drug discovery and process development pipelines, ensuring reliable and scalable synthesis routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new chemical entities (NCEs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Process Chemistry & Scale-Up: Serves as a defined starting material or intermediate for the GMP-compliant synthesis of active pharmaceutical ingredients (APIs) during clinical and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and exploring new biological pathways.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide, 4,5,6,7-Tetrahydro-2-(4-Phenoxyphenyl)-7-(4-Piperidinyl)-, (7S)-
CAS No.	1633352-71-2
Molecular Formula	C24H27N5O2
Molecular Weight	417.51 g/mol
Synonyms	(7S)-4,5,6,7-Tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; (7S)-7-(Piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide; UNII-9F8S6A6D4I; 9F8S6A6D4I; BDBM50388895; ZINC000006714947; AKOS025147065; CHEMBL3185222
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide intermediate is produced under strict quality management systems, with testing protocols designed to meet the exacting standards of pharmaceutical development. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure identity, strength, quality, and purity. Certificates of Analysis (COA) with full analytical data from HPLC, NMR, and MS are provided to support regulatory filings and ensure supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.