Description

6-Chloroindolizine is a versatile and synthetically valuable halogenated heterocyclic building block. Its core indolizine scaffold, functionalized with a reactive chlorine atom, makes it a critical intermediate for constructing complex molecular architectures in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, such as herbicides and fungicides, leveraging its heterocyclic bioactivity.
• Ligand & Catalyst Development: Acts as a foundational structure for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science: Employed in the research of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs) due to its electron-rich π-system.
• Chemical Biology: Utilized as a molecular probe or a tagging reagent in bioconjugation and proteomics research.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry within R&D laboratories.

Basic Information

Product Name	6-Chloroindolizine
CAS No.	1632285-97-2
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	6-Chloroindolizine; 6-Chloro-1-azaindene; Indolizine, 6-chloro-; 6-Chloro-1H-indolizine; 6-Chloro-1-azaindole (non-standard); 6-Cl-indolizine
EINECS	Contact for details

Quality Control

Our 6-Chloroindolizine is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We can support development projects with material meeting custom purity specifications, including research-grade and GMP-starting material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.