Description

Pf-06446846 is a high-purity chemical compound identified by CAS No. 1632250-49-7, serving as a critical intermediate or active pharmaceutical ingredient (API) in advanced research and development. This compound is valued for its precise chemical structure and consistent performance in complex synthetic pathways. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and contract development and manufacturing organizations (CDMOs) engaged in the discovery and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of target drug molecules and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or reagent in pharmacological and metabolic studies to investigate biological pathways.
• Preclinical Development: Employed in the formulation and testing of new drug candidates during early-stage development.
• Process Chemistry: Integral to scale-up and optimization of synthetic routes in pilot plants and commercial manufacturing.
• Contract Manufacturing: Supplied to CDMOs for the production of specialized compounds under cGMP conditions.
• Analytical Standard: Serves as a high-purity standard for method development and validation in quality control laboratories.

Basic Information

Product Name	Pf-06446846
CAS No.	1632250-49-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF06446846; 1632250-49-7; UNII-8JQ5607E5S; 8JQ5607E5S; CHEMBL2103875; BDBM50388851; AKOS009158046; (IUPAC name to be confirmed)
EINECS	Contact for details

Quality Control

Our Pf-06446846 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), related substances, residual solvents, and other critical parameters is provided with every shipment. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.