Description

(S)-4-Phenyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole CAS NO 1632140-87-4 is a high-value, chiral oxazoline derivative characterized by its phenyl and pyrazinyl substituents. This compound serves as a sophisticated building block and chiral ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily required by pharmaceutical R&D laboratories, agrochemical manufacturers, and advanced material scientists for developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalysis: Acts as a chiral ligand or auxiliary in transition metal-catalyzed reactions, such as asymmetric hydrogenation or cycloaddition, to induce high enantioselectivity.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science: A building block for creating chiral polymers or liquid crystals with specific optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-4-Phenyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole
CAS No.	1632140-87-4
Molecular Formula	C₁₃H₁₁N₃O
Molecular Weight	225.25 g/mol
Synonyms	(S)-4-Phenyl-2-(pyrazin-2-yl)-4,5-dihydrooxazole; (S)-2-(Pyrazin-2-yl)-4-phenyl-4,5-dihydrooxazole; (4S)-4-Phenyl-2-(pyrazin-2-yl)-4,5-dihydro-1,3-oxazole; (S)-4-Phenyl-2-pyrazin-2-yl-4,5-dihydrooxazole; Chiral Pyrazinyl Oxazoline; (S)-Phenyl(pyrazinyl)dihydrooxazole
EINECS	Contact for details

Quality Control

Our (S)-4-Phenyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.