Description

(S)-4-Benzyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole is a high-purity chiral oxazoline derivative, a crucial building block in modern asymmetric synthesis and pharmaceutical research. Its value lies in its role as a versatile ligand precursor and intermediate for constructing complex molecules with high stereoselectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise chiral control in their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis: Serves as a precursor for chiral oxazoline ligands used in transition metal-catalyzed reactions, such as asymmetric hydrogenation, cyclopropanation, and Diels-Alder reactions.
• Agrochemical Research: Employed in the synthesis of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the development of chiral polymers and liquid crystals with specific optical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new catalytic systems in university and corporate laboratories.

Basic Information

Product Name	(S)-4-Benzyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole
CAS No.	1632140-86-3
Molecular Formula	C₁₄H₁₃N₃O
Molecular Weight	239.27 g/mol
Synonyms	(S)-4-Benzyl-2-(pyrazin-2-yl)-4,5-dihydrooxazole; (S)-4-Benzyl-2-pyrazin-2-yl-4,5-dihydro-1,3-oxazole; (S)-2-(2-Pyrazinyl)-4-benzyl-2-oxazoline; (S)-4-Benzyl-2-(2-pyrazinyl)-2-oxazoline; (S)-4-Benzyl-2-(pyrazin-2-yl)-2-oxazoline; (S)-4-Benzyl-2-(2-pyrazinyl)-4,5-dihydrooxazole; (S)-4-Benzyl-2-(2-pyrazinyl)-δ²-oxazoline
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-2-(Pyrazin-2-Yl)-4,5-Dihydrooxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.