Description

Ethyl 2-(3-Methylpiperidin-4-Yl)Acetate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in its stable hydrochloride salt form. This compound is a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and other therapeutic agents. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of complex drug molecules targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and route scouting for API manufacturing.
• Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in regulatory filings.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and enzyme interactions in preclinical studies.

Basic Information

Product Name	Ethyl 2-(3-Methylpiperidin-4-Yl)Acetate Hydrochloride
CAS No.	1630907-26-4
Molecular Formula	C10H20ClNO2
Molecular Weight	221.73 g/mol
Synonyms	Ethyl 2-(3-Methyl-4-piperidinyl)acetate hydrochloride; 4-Piperidineacetic acid, 3-methyl-, ethyl ester, hydrochloride; Ethyl (3-methylpiperidin-4-yl)acetate hydrochloride; 2-(3-Methylpiperidin-4-yl)acetic acid ethyl ester hydrochloride; Ethyl 3-methyl-4-piperidinylacetate hydrochloride; 1630907-26-4; Ethyl 2-(3-methyl-4-piperidyl)acetate HCl
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Methylpiperidin-4-Yl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) with full traceability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.