Description

Trifluoroacetic Acid CAS NO 1630906-83-0 is a highly versatile and potent fluorinated organic acid. It serves as a critical reagent and solvent in advanced organic synthesis, particularly valued for its strong acidity and excellent solvating properties. This product is essential for pharmaceutical manufacturers, agrochemical researchers, and material scientists engaged in peptide synthesis, protecting group removal, and the production of specialty polymers.

Application

• Pharmaceutical Synthesis: As a key reagent for the cleavage of protecting groups (e.g., Boc, t-butyl esters) in peptide and oligonucleotide synthesis.
• Organic Chemistry Reagent: Utilized as a strong acid catalyst in various condensation, esterification, and rearrangement reactions.
• Analytical Chemistry: Employed as a volatile ion-pairing agent and mobile phase modifier in High-Performance Liquid Chromatography (HPLC), especially for biomolecule separation.
• Polymer Industry: Acts as a solvent and catalyst in the production of specialty fluoropolymers and other high-performance materials.
• Agrochemical Manufacturing: Used in the synthesis of complex fluorinated pesticide and herbicide intermediates.
• Laboratory Solvent: Serves as a powerful solvent for resins, dyes, and other organic compounds due to its high polarity and volatility.

Basic Information

Product Name	Trifluoroacetic Acid
CAS No.	1630906-83-0
Molecular Formula	C2HF3O2
Molecular Weight	114.02 g/mol
Synonyms	Trifluoroethanoic Acid; Perfluoroacetic Acid; TFA; CF3COOH; 2,2,2-Trifluoroacetic Acid; Acetic Acid, Trifluoro-; Kyselina Trifluoroctova; Trifluoressigsaeure
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile and strong acid/organic solvent nature, containers must be kept tightly sealed to prevent moisture absorption and fume release.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Refractive Index (n20D)	1.2850 - 1.2890
Density (20°C)	1.480 - 1.490 g/mL
Residue on Evaporation	≤ 0.005%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.