Description

tert-Butyl Octahydropiperazino[2,1-C]Morpholine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, where precise chemical synthesis and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused piperazine-morpholine scaffolds, which are valuable pharmacophores.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl Octahydropiperazino[2,1-C]Morpholine-8-Carboxylate
CAS No.	1630906-78-3
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	tert-Butyl 1,2,3,4,6,7,8,8a-Octahydropiperazino[2,1-c][1,4]oxazine-8-carboxylate; 8-(tert-Butoxycarbonyl)-1,2,3,4,6,7,8,8a-octahydropiperazino[2,1-c][1,4]oxazine; BOC-Protected Octahydropiperazinomorpholine; 8-Boc-Octahydropiperazino[2,1-c]morpholine; tert-Butyl 2,3,4,6,7,8-hexahydro-1H-[1,4]oxazino[4,3-a]pyrazine-8-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl Octahydropiperazino[2,1-C]Morpholine-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.