Description

Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern organic synthesis. Its complex heterocyclic structure makes it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and novel chemical entities.
• Drug Discovery & Medicinal Chemistry: Serves as a privileged scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Research & Development (R&D): Used in route scouting, optimization, and scale-up activities for API manufacturing.
• Academic & Industrial Research: Employed in synthetic methodology development and the study of heterocyclic chemistry.
• Custom Synthesis: A starting material for the preparation of more complex, tailored molecules for specific client projects.

Basic Information

Product Name	Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One Hydrochloride
CAS No.	1628557-06-1
Molecular Formula	C7H13N3O·HCl
Molecular Weight	191.66 g/mol (Free base: 155.20 g/mol)
Synonyms	1,2,3,3a,4,6-Hexahydropyrrolo[1,2-a]pyrazin-4-one hydrochloride; Hexahydro-1H-pyrrolo[1,2-a]pyrazin-4-one hydrochloride; 4-Oxo-hexahydro-pyrrolo[1,2-a]pyrazine hydrochloride; Pyrrolo[1,2-a]pyrazin-4-one, hexahydro-, hydrochloride; CAS 1628557-06-1
EINECS	Contact for details

Quality Control

Our Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.