Description

tert-Butyl 2-Methyl-5-Oxopiperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for its utility in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Employed in the design and synthesis of peptidomimetics and constrained peptides due to its piperazine core.
• Agrochemical Development: Serves as a precursor in the creation of new crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-Methyl-5-Oxopiperazine-1-Carboxylate
CAS No.	1627748-01-9
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	1-Boc-2-methyl-5-oxopiperazine; tert-Butyl 2-methyl-5-oxo-1-piperazinecarboxylate; 2-Methyl-5-oxopiperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-methyl-5-oxopiperazine; Boc-2-methyl-5-oxopiperazine; 2-Methyl-1,4-diazepan-5-one-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-5-Oxopiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.