Description

Remodelin Hydrobromide is a high-purity, small-molecule compound with the CAS registry number 1622921-15-6. This compound is of significant interest in advanced life science research, particularly as a potent and selective inhibitor of NAT10, an enzyme implicated in cellular aging and disease pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on aging research, oncology, and metabolic disorders.

Application

• Biochemical Research: Used as a key tool compound in studies investigating the role of NAT10 (N-acetyltransferase 10) in cellular processes such as senescence, DNA damage response, and RNA modification.
• Drug Discovery & Development: Serves as a lead compound or pharmacological probe in preclinical research for developing novel therapeutics targeting age-related diseases and certain cancers.
• Academic Studies: Employed in university and institutional labs to explore fundamental mechanisms of aging (geroscience) and to validate new therapeutic hypotheses.
• In Vitro & Cell-Based Assays: Applied in high-throughput screening (HTS) and functional assays to study compound efficacy and mechanism of action in relevant cell models.
• Reference Standard: Supplied as a certified reference material for analytical method development, quality control, and validation in research settings.

Basic Information

Product Name	Remodelin Hydrobromide
CAS No.	1622921-15-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Remodelin HBr; NAT10 Inhibitor; 4-[(4-fluorophenyl)amino]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinoline-3-carbonitrile hydrobromide; 6-Methoxy-7-[3-(1-pyrrolidinyl)propoxy]-4-[(4-fluorophenyl)amino]-3-quinolinecarbonitrile hydrobromide
EINECS	Contact for details

Quality Control

Our Remodelin Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.