Description

(S)-5-Oxopiperazine-2-Carboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in producing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Peptide Mimetic Synthesis: Used in the construction of peptidomimetics and constrained peptide analogs to improve metabolic stability and bioavailability.
• Chemical Biology Research: Serves as a valuable scaffold or precursor in the study of enzyme-substrate interactions and biochemical pathways.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective synthesis to introduce the (S)-configured piperazine carboxylic acid moiety.
• API Development: Integral to the process development and scale-up synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-5-Oxopiperazine-2-Carboxylic Acid Hydrochloride
CAS No.	1621961-57-6
Molecular Formula	C5H9N2O3•HCl
Molecular Weight	196.60 g/mol
Synonyms	(2S)-5-Oxo-2-piperazinecarboxylic acid hydrochloride; (S)-Piperazine-2-carboxylic acid, 5-oxo-, hydrochloride; L-5-Oxopiperazine-2-carboxylic acid hydrochloride; (S)-5-Oxopiperazine-2-carboxylic acid HCl; 2-Piperazinecarboxylic acid, 5-oxo-, (2S)-, hydrochloride; (S)-2-Carboxy-5-oxopiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-5-Oxopiperazine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.