Description

tert-Butyl N-(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates, particularly in oncology and anti-inflammatory research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a sulfonamide and protected amine functionality.
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the preparation of more complex, target-specific molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	tert-Butyl N-(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate
CAS No.	1621083-43-9
Molecular Formula	C19H27N5O5S
Molecular Weight	437.51 g/mol
Synonyms	Boc-protected sulfonamido pyrazine intermediate; tert-Butyl (3-{5-[(4-aminophenyl)sulfonyl]amino-6-methoxypyrazin-2-yl}propyl)carbamate; 1,1-Dimethylethyl N-[3-[5-[[(4-aminophenyl)sulfonyl]amino]-6-methoxy-2-pyrazinyl]propyl]carbamate; 1621083-43-9; 5-((4-Aminophenyl)sulfonamido)-6-methoxy-N-(3-((tert-butoxycarbonyl)amino)propyl)pyrazine-2-carboxamide (related); Sulfonamide-pyrazine building block
EINECS	Contact for details

Quality Control

Our tert-Butyl N-(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.