Description

1-(4-(5-(5-Amino-6-(5-tert-Butyl-1,3,4-Oxadiazol-2-Yl)Pyrazin-2-Yl)-1-Ethyl-1H-1,2,4-Triazol-3-Yl)Piperidin-1-Yl)-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propan-1-One is a sophisticated heterocyclic organic compound designed for advanced research and development. This high-purity intermediate is critical for medicinal chemistry programs, particularly in the synthesis of novel therapeutic agents targeting complex disease pathways. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates in oncology, virology, and central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with potential biological activity.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled compounds or molecular probes used in biochemical assays and diagnostic research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored drug discovery projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-(4-(5-(5-Amino-6-(5-tert-Butyl-1,3,4-Oxadiazol-2-Yl)Pyrazin-2-Yl)-1-Ethyl-1H-1,2,4-Triazol-3-Yl)Piperidin-1-Yl)-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propan-1-One
CAS No.	1620576-86-4
Molecular Formula	C28H40N8O3
Molecular Weight	536.67 g/mol
Synonyms	CAS 1620576-86-4; 1-[4-[5-[5-Amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-1-ethyl-1,2,4-triazol-3-yl]piperidin-1-yl]-3-(oxan-2-yloxy)propan-1-one; 3-(Tetrahydro-2H-pyran-2-yloxy)-1-[4-[5-[5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl]-1-ethyl-1H-1,2,4-triazol-3-yl]-1-piperidinyl]-1-propanone; Propan-1-one derivative with CAS 1620576-86-4; THP-protected oxadiazolyl-triazolyl-piperidine propanone intermediate
EINECS	Contact for details

Quality Control

Our 1-(4-(5-(5-Amino-6-(5-tert-Butyl-1,3,4-Oxadiazol-2-Yl)Pyrazin-2-Yl)-1-Ethyl-1H-1,2,4-Triazol-3-Yl)Piperidin-1-Yl)-3-(Tetrahydro-2H-Pyran-2-Yloxy)Propan-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization where applicable. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.