Description

5-Bromo-3-(Piperazin-1-Yl)Pyrazin-2-Amine 2,2,2-Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant value for its role as a key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapeutic research. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions focused on medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing biochemical probes to study specific biological pathways.
• Contract Manufacturing: Supplied to CMOs for the cGMP-compliant production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	5-Bromo-3-(Piperazin-1-Yl)Pyrazin-2-Amine 2,2,2-Trifluoroacetate
CAS No.	1620569-21-2
Molecular Formula	C10H12BrF3N6O2
Molecular Weight	385.15 g/mol
Synonyms	5-Bromo-3-(piperazin-1-yl)pyrazin-2-amine trifluoroacetate; 2-Pyrazinamine, 5-bromo-3-(1-piperazinyl)-, 2,2,2-trifluoroacetate (1:1); 5-Bromo-3-piperazin-1-yl-pyrazin-2-ylamine trifluoroacetate; 1620569-21-2; 5-Bromo-3-(1-piperazinyl)-2-pyrazinamine trifluoroacetate; 5-Bromo-3-(piperazin-1-yl)-2-pyrazinamine 2,2,2-trifluoroacetate
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(Piperazin-1-Yl)Pyrazin-2-Amine 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.