Description

4-Chloro-2-(4-Methylphenyl)Pyrazolo-[1,5-A]Pyrazine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrazine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Kinase Inhibitor Development: A valuable scaffold for creating potent and selective kinase inhibitors, a major class in oncology.
• Chemical Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-Chloro-2-(4-Methylphenyl)Pyrazolo-[1,5-A]Pyrazine-3-Carbaldehyde
CAS No.	1610377-21-3
Molecular Formula	C14H10ClN3O
Molecular Weight	271.70 g/mol
Synonyms	4-Chloro-2-(p-tolyl)pyrazolo[1,5-a]pyrazine-3-carboxaldehyde; 2-(4-Methylphenyl)-4-chloropyrazolo[1,5-a]pyrazine-3-carbaldehyde; 4-Chloro-2-(4-methylphenyl)pyrazolo[1,5-a]pyrazine-3-carbaldehyde; 1610377-21-3; 4-Chloro-2-(p-tolyl)pyrazolo[1,5-a]pyrazine-3-carbaldehyde; Pyrazolo[1,5-a]pyrazine-3-carbaldehyde, 4-chloro-2-(4-methylphenyl)-; 4-Chloro-2-(4-methylphenyl)-1,5-dihydropyrazolo[1,5-a]pyrazine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Methylphenyl)Pyrazolo-[1,5-A]Pyrazine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.