Description

2-(4-Methoxyphenyl)-4-Oxo-4,5-Dihydro-Pyrazolo[1,5-A]Pyrazine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate with the CAS number 1610377-12-2. This heterocyclic aldehyde is a critical building block in modern medicinal chemistry, valued for its unique fused pyrazolo-pyrazine core which enables the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly for oncology and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic libraries via its reactive aldehyde and carbonyl functionalities.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-(4-Methoxyphenyl)-4-Oxo-4,5-Dihydro-Pyrazolo[1,5-A]Pyrazine-3-Carbaldehyde
CAS No.	1610377-12-2
Molecular Formula	C14H11N3O3
Molecular Weight	269.26 g/mol
Synonyms	2-(4-Methoxyphenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-3-carboxaldehyde; 4,5-Dihydro-2-(4-methoxyphenyl)-4-oxopyrazolo[1,5-a]pyrazine-3-carbaldehyde; Pyrazolo[1,5-a]pyrazine-3-carbaldehyde, 4,5-dihydro-2-(4-methoxyphenyl)-4-oxo-; 1610377-12-2; 2-(4-Methoxyphenyl)-4-oxo-4,5-dihydro-1H-pyrazolo[1,5-a]pyrazine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxyphenyl)-4-Oxo-4,5-Dihydro-Pyrazolo[1,5-A]Pyrazine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.