Description

4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecules in drug discovery programs.
• Chemical Synthesis: Used in organic synthesis to introduce the tetrahydropyrazolopyrazine core into target molecules.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carbonitrile Hydrochloride
CAS No.	1609406-44-1
Molecular Formula	C8H9N4·HCl
Molecular Weight	196.64 g/mol (Free base: 160.18 g/mol)
Synonyms	4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carbonitrile hydrochloride; 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine-2-carbonitrile HCl; 4,5,6,7-Tetrahydro-2-pyrazolo[1,5-a]pyrazinecarbonitrile hydrochloride; Pyrazolo[1,5-a]pyrazine-2-carbonitrile, 4,5,6,7-tetrahydro-, hydrochloride; 1609406-44-1; UNII-8K9V3B6A2T
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.