Description

(2-Chloro-4-Nitrophenyl)(Piperazin-1-Yl)Methanone Hydrochloride is a high-purity, synthetically valuable chemical building block. This compound is essential for advanced research and development in pharmaceutical chemistry, serving as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories, process development chemists, and manufacturers in the life sciences sector seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex molecules with potential pharmacological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• API Development: Serves as a building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized to create specialized probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and novel methodology development.

Basic Information

Product Name	(2-Chloro-4-Nitrophenyl)(Piperazin-1-Yl)Methanone Hydrochloride
CAS No.	1605138-92-8
Molecular Formula	C11H12ClN3O3 • HCl
Molecular Weight	306.15 g/mol (Free base: 269.69 g/mol)
Synonyms	1-[(2-Chloro-4-nitrophenyl)carbonyl]piperazine hydrochloride; 2-Chloro-4-nitrobenzoic acid piperazide hydrochloride; (2-Chloro-4-nitrophenyl)(piperazin-1-yl)methanone HCl; Piperazine, 1-[(2-chloro-4-nitrophenyl)carbonyl]-, hydrochloride; 1605138-92-8; (2-Chloro-4-nitrobenzoyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Chloro-4-Nitrophenyl)(Piperazin-1-Yl)Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.