Description

Methyl 6-Iodopyrazine-2-Carboxylate is a high-value iodinated pyrazine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is prized for its reactive iodine atom and ester functionality, enabling precise molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the pyrazine scaffold.
• Material Science Research: Precursor for creating functionalized heterocyclic ligands and organic electronic materials.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	Methyl 6-Iodopyrazine-2-Carboxylate
CAS No.	1603172-68-4
Molecular Formula	C6H5IN2O2
Molecular Weight	264.02 g/mol
Synonyms	6-Iodopyrazine-2-carboxylic acid methyl ester; Methyl 6-iodo-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 6-iodo-, methyl ester; Methyl 6-iodopyrazinecarboxylate; 6-Iodo-2-pyrazinecarboxylic acid methyl ester; Methyl 6-iodo-2-pyrazinecarboxylate; Methyl 6-iodopyrazine-2-carboxylate; 1603172-68-4
EINECS	Contact for details

Quality Control

Every batch of Methyl 6-Iodopyrazine-2-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and ensure compliance with relevant industry standards for research and development materials. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.