Description

tert-Butyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-C]Pyrrole-2(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the class of bicyclic pyrrolidine derivatives. This compound is of significant value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams and process chemists in the pharmaceutical and biotechnology industries for the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing constrained, three-dimensional molecular architectures to improve drug-like properties.
• Asymmetric Catalysis Research: Employed as a precursor or ligand in the development of new catalytic systems due to its rigid, bicyclic structure.
• Agrochemical Development: Potential application in creating novel, high-performance crop protection agents with specific stereochemistry.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for method development and exploratory synthesis projects.

Basic Information

Product Name	tert-Butyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-C]Pyrrole-2(1H)-Carboxylate
CAS No.	1588507-39-4
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl (3aR,6aR)-Hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate; (3aR,6aR)-1-(tert-Butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrole; (3aR,6aR)-N-Boc-2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole; (3aR,6aR)-1-Boc-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole; tert-Butyl (3aR,6aR)-octahydro-1H-pyrrolo[3,4-c]pyrrole-1-carboxylate; (3aR,6aR)-1-Boc-octahydro-1H-pyrrolo[3,4-c]pyrrole; Bicyclic Pyrrolidine Derivative; Chiral Pyrrolidine Building Block
EINECS	Contact for details

Quality Control

Our tert-Butyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-C]Pyrrole-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.