Description

(R)-1-Benzyl-2-Methylpiperazine Hydrochloride CAS NO 1588480-39-0 is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its primary value lies in its role as a key chiral intermediate for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. This compound is essential for research and manufacturing organizations in the pharmaceutical and biotechnology sectors requiring enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel APIs, especially in neurological and psychiatric drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of commercial-scale synthetic routes for chiral drugs.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	(R)-1-Benzyl-2-Methylpiperazine Hydrochloride
CAS No.	1588480-39-0
Molecular Formula	C12H18N2·HCl
Molecular Weight	226.74 g/mol
Synonyms	(R)-1-Benzyl-2-methylpiperazine HCl; (R)-1-Benzyl-2-methylpiperazine hydrochloride; (R)-2-Methyl-1-benzylpiperazine hydrochloride; (R)-1-Bn-2-Me-piperazine HCl; (R)-BMP HCl; (R)-1-Benzyl-2-methylpiperazine monohydrochloride; (R)-enantiomer of 1-Benzyl-2-methylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-2-Methylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.