Description

Pyrazine-2,5-Diamine Dihydrochloride is a high-purity organic salt derivative of a pyrazine diamine, serving as a critical building block in advanced chemical synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex heterocyclic systems, particularly in pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with pyrazine or fused heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage the pyrazine scaffold for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Building block for the development of organic electronic materials, conductive polymers, and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and organic pigments due to the chromophoric nature of the pyrazine ring.
• Bioconjugation and Probe Development: The amine functional groups make it suitable for bioconjugation chemistry in diagnostic probe and biomarker development.

Basic Information

Product Name	Pyrazine-2,5-Diamine Dihydrochloride
CAS No.	1588441-32-0
Molecular Formula	C4H8N4·2HCl
Molecular Weight	197.06 g/mol
Synonyms	2,5-Diaminopyrazine Dihydrochloride; Pyrazine-2,5-diyldiamine Dihydrochloride; 2,5-Pyrazinediamine Dihydrochloride; 1,4-Diazine-2,5-diamine Dihydrochloride; 2,5-Diamino-1,4-diazine Dihydrochloride; NSC 403679 Dihydrochloride; Pyrazine-2,5-diamine, Dihydrochloride
EINECS	Contact for details

Quality Control

Our Pyrazine-2,5-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide full traceability and Certificates of Analysis (COA) for every shipment, ensuring compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.