Description

Ethyl 1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1567995-93-0. This heterocyclic compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting specific biological pathways.
• API Development: Serves as a core scaffold or building block for the research and production of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic value.
• Contract Manufacturing (CDMO): Supplied to Contract Development and Manufacturing Organizations for custom synthesis projects and scale-up activities.
• Bioconjugation Chemistry: Potential use in creating specialized linkers or payloads for antibody-drug conjugates (ADCs) and other targeted therapies.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Ethyl 1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazine-4-Carboxylate
CAS No.	1567995-93-0
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	Ethyl 1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate; 4-Carbethoxy-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione; Pyrrolo[1,2-a]pyrazine-4-carboxylic acid, 1,2,3,4-tetrahydro-1,3-dioxo-, ethyl ester; CAS 1567995-93-0; Ethyl tetrahydropyrrolopyrazinedicarboxylate derivative; 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-1,3-dione-4-carboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Our Ethyl 1,3-Dioxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazine-4-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with cGMP and ISO guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.