Description

2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolo-pyrazinone chemical class. This compound is of significant commercial interest for its role as a key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology. Pharmaceutical R&D teams, fine chemical manufacturers, and contract research organizations (CROs) require this material for lead optimization and process chemistry development.

Application

This specialized intermediate is designed for high-value synthesis applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in lead compound libraries for structure-activity relationship (SAR) studies and hit-to-lead optimization programs.
• Process Development: Serves as a key starting material (KSM) or advanced intermediate in scaling up API manufacturing processes under GMP conditions.
• Biochemical Research: Potential use as a tool compound or probe for investigating biological pathways and target validation.
• Custom Synthesis: A versatile scaffold for contract manufacturing organizations (CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One
CAS No.	1553968-38-9
Molecular Formula	C13H10FN3O
Molecular Weight	243.24 g/mol
Synonyms	2-(4-Fluorophenyl)-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrazin-4-one; 6,7-Dihydro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4(5H)-one; 1553968-38-9; 2-(p-Fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one; Pyrazolo[1,5-a]pyrazin-4(5H)-one, 6,7-dihydro-2-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.