Description

6-Chloro-2-Methylimidazo[1,2-A]Pyrazine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, especially in oncology and antiviral therapeutic areas.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its versatile imidazopyrazine core.
• Research & Development (R&D): Essential for academic and industrial R&D labs focusing on heterocyclic chemistry and new molecular entity (NME) discovery.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a sophisticated intermediate in the multi-step synthesis of complex, high-value APIs under GMP conditions.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs and CDMOs for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	6-Chloro-2-Methylimidazo[1,2-A]Pyrazine-3-Carboxylic Acid
CAS No.	1553646-86-8
Molecular Formula	C9H6ClN3O2
Molecular Weight	223.62 g/mol
Synonyms	6-Chloro-2-methylimidazo[1,2-a]pyrazine-3-carboxylic acid; 2-Methyl-6-chloroimidazo[1,2-a]pyrazine-3-carboxylic acid; Imidazo[1,2-a]pyrazine-3-carboxylic acid, 6-chloro-2-methyl-; 1553646-86-8; 6-Chloro-2-methyl-imidazo[1,2-a]pyrazine-3-carboxylic acid; 6-Chloro-2-methylimidazo[1,2-a]pyrazine-3-carboxylate (acid form)
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Methylimidazo[1,2-A]Pyrazine-3-Carboxylic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.