Description

Br-PEG8-OH is a monodisperse, bifunctional polyethylene glycol (PEG) derivative featuring a bromo group at one terminus and a hydroxyl group at the other. This unique structure makes it a highly versatile intermediate for bioconjugation, linker synthesis, and the creation of functionalized materials. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise, high-purity building blocks for drug delivery systems, diagnostic probes, and surface modifications.

Application

• Bioconjugation Linker: Used to attach drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles for targeted delivery and diagnostics.
• Polymer Chemistry Intermediate: Serves as a macro-initiator or functional monomer for synthesizing block copolymers and PEGylated materials with tailored properties.
• Surface Functionalization: The bromo group allows for covalent attachment to surfaces, while the PEG chain provides anti-fouling and stealth properties for biosensors and medical devices.
• Cross-linking Agent: Utilized in the preparation of hydrogels and polymer networks where controlled spacing and hydrophilicity are required.
• Pharmaceutical Research: A key building block in the development of prodrugs and antibody-drug conjugates (ADCs) to improve solubility and pharmacokinetics.
• Material Science: Incorporated into coatings and composites to enhance biocompatibility and reduce non-specific binding.

Basic Information

Product Name	Br-PEG8-OH
CAS No.	1527515-88-3
Molecular Formula	C17H35BrO9
Molecular Weight	463.36 g/mol
Synonyms	8-Bromo-3,6,9,12,15,18,21-heptaoxatricosan-1-ol; 1-Bromo-3,6,9,12,15,18,21-heptaoxatricosan-23-ol; Bromo-PEG8-alcohol; Bromo octaethylene glycol; α-Bromo-ω-hydroxy-octa(ethylene glycol); Br-(CH2CH2O)8-OH; Bromo-terminated PEG8; Bromo-PEG8-OH
EINECS	Contact for details

Quality Control

Our Br-PEG8-OH is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Molecular Weight (MS)	463.36 ± 2 Da

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.