Description

1-Azaspiro[3.3]heptane hemioxalate is a high-value, nitrogen-containing spirocyclic building block with the CAS registry number 1523571-15-4. This compound is critical for medicinal chemistry and pharmaceutical research, enabling the synthesis of novel molecular architectures with potential therapeutic activity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex, three-dimensional scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Medicinal Chemistry Building Block: Used to introduce the constrained 1-azaspiro[3.3]heptane motif, which can improve the potency, selectivity, and metabolic stability of drug candidates.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides with new modes of action.
• Ligand and Catalyst Development: Utilized in organocatalysis and as a component in chiral ligands for asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and protein-protein interactions.
• Advanced Material Synthesis: A potential monomer or cross-linker for creating polymers with unique thermal and mechanical properties.

Basic Information

Product Name	1-Azaspiro[3.3]heptane Hemioxalate
CAS No.	1523571-15-4
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	1-Azaspiro[3.3]heptane, hemioxalate salt; 1-Aza-3-oxaspiro[3.3]heptane hemioxalate (incorrect but common); 1-Azaspiro[3.3]heptane oxalate (1:0.5); 2,6-Diazaspiro[3.3]heptane hemioxalate (related); Spiro[2.2]pentane-1-carbonitrile, 1-amino- (precursor); Azaspiroheptane hemioxalate; 1523571-15-4; CAS 1523571-15-4
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[3.3]heptane hemioxalate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.