Description

(2S,5R)-1,2,5-Trimethylpiperazine: Oxalic Acid is a high-purity, non-racemic chiral salt formed from a specific stereoisomer of trimethylpiperazine and oxalic acid. This compound is valued as a critical chiral intermediate and resolving agent in the synthesis of complex pharmaceutical molecules, enabling the production of enantiomerically pure active ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing advanced therapeutics, including central nervous system (CNS) agents and other specialized drugs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the asymmetric synthesis of novel drug candidates.
• Chiral Resolving Agent: Used for the separation of racemic mixtures to obtain single enantiomers with desired biological activity.
• Catalyst Ligand Precursor: Acts as a precursor for ligands in asymmetric catalysis, enhancing reaction selectivity.
• Advanced Organic Synthesis: Employed in research and development for constructing complex, stereochemically defined molecular architectures.
• Reference Standard: Utilized as an analytical standard for method development and quality control in chiral analysis.

Basic Information

Product Name	(2S,5R)-1,2,5-Trimethylpiperazine: Oxalic Acid
CAS No.	1523541-99-2
Molecular Formula	C9H18N2 • C2H2O4
Molecular Weight	274.29 g/mol
Synonyms	(2S,5R)-1,2,5-Trimethylpiperazine Oxalate; (2S,5R)-1,2,5-Trimethylpiperazine ethanedioate; 1,2,5-Trimethylpiperazine oxalic acid salt; (2S,5R)-TMP oxalate; (2S,5R)-1,2,5-TMP Oxalic Acid Salt; (2S,5R)-1,2,5-Trimethylpiperazine dihydrogen oxalate; Piperazine, 1,2,5-trimethyl-, (2S,5R)-, oxalate (1:1)
EINECS	Contact for details

Quality Control

Our (2S,5R)-1,2,5-Trimethylpiperazine: Oxalic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.