Description

2-Ethyl-4,4-Difluorobutanoic Acid is a fluorinated carboxylic acid building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms and an ethyl side chain, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly where fluorine substitution is used to modulate metabolic stability, bioavailability, and receptor binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro motif can enhance activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated compounds used in liquid crystal displays (LCDs) and other electronic applications requiring specific dielectric properties.
• Organic Synthesis Building Block: Employed in various organic reactions, including esterifications, amide couplings, and reductions, to introduce a fluorinated acid moiety into more complex molecular architectures.
• Polymer Modification: Can be used to synthesize fluorinated monomers or as a modifier to impart unique properties like oil repellency, chemical resistance, or low surface energy to polymers.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	2-Ethyl-4,4-Difluorobutanoic Acid
CAS No.	1511599-27-1
Molecular Formula	C6H10F2O2
Molecular Weight	152.14 g/mol
Synonyms	4,4-Difluoro-2-ethylbutanoic Acid; 2-Ethyl-4,4-difluorobutanoic Acid; Butanoic acid, 4,4-difluoro-2-ethyl-; α-Ethyl-γ,γ-difluorobutyric Acid; γ,γ-Difluoro-α-ethylbutyric Acid; 4,4-Difluoro-2-ethylbutyric Acid; 1511599-27-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Ethyl-4,4-Difluorobutanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, maintaining the container under an inert atmosphere (e.g., nitrogen or argon) is recommended to preserve product integrity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.