Description

1,2,4-Triazolo[4,3-A]Pyrazine-7(8H)-Acetic Acid, 5,6-Dihydro-3-(Trifluoromethyl)- is a high-value, heterocyclic organic compound featuring a fused triazolopyrazine core and a trifluoromethyl group. This structure makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily sought after by research organizations and fine chemical manufacturers engaged in drug discovery and development, particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the triazolopyrazine scaffold.
• Material Science: Potential precursor for specialty polymers or ligands in catalytic systems due to its nitrogen-rich heterocyclic structure.
• Academic & R&D: Serves as a standard or starting material in organic synthesis and methodological studies within university and corporate laboratories.
• Bioconjugation Chemistry: The acetic acid moiety allows for potential use in creating conjugates for biochemical probes or targeted therapies.

Basic Information

Product Name	1,2,4-Triazolo[4,3-A]Pyrazine-7(8H)-Acetic Acid, 5,6-Dihydro-3-(Trifluoromethyl)-
CAS No.	1496395-30-2
Molecular Formula	C8H7F3N4O2
Molecular Weight	248.16 g/mol
Synonyms	5,6-Dihydro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-acetic acid; 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-acetic acid; 1,2,4-Triazolo[4,3-a]pyrazine-7-acetic acid, 5,6-dihydro-3-(trifluoromethyl)-; 1496395-30-2; Triazolopyrazine acetic acid derivative
EINECS	Contact for details

Quality Control

Our production of 1,2,4-Triazolo[4,3-A]Pyrazine-7(8H)-Acetic Acid, 5,6-Dihydro-3-(Trifluoromethyl)- adheres to stringent cGMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.