Description

1-[4-[[(2S,4S)-2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-Ylmethyl)-1,3-Dioxolan-4-Yl]Methoxy]Phenyl]-4-Propan-2-Ylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its complex stereochemistry and functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the antifungal and therapeutic agent development sectors. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on creating next-generation treatments.

Application

• Key Intermediate in Antifungal API Synthesis: Serves as a crucial building block in the production of advanced triazole-based antifungal agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new chemical entities with targeted biological activity.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of candidate drugs.
• Fine Chemical Production: Integral to the synthesis of complex, high-value specialty chemicals for the life sciences industry.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of proprietary drug substances under cGMP.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Item	Detail
Product Name	1-[4-[[(2S,4S)-2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-Ylmethyl)-1,3-Dioxolan-4-Yl]Methoxy]Phenyl]-4-Propan-2-Ylpiperazine
CAS No.	1486497-66-8
Molecular Formula	C27H31Cl2N5O3
Molecular Weight	544.47 g/mol
Synonyms	(2S,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-Triazol-1-ylmethyl)-4-[4-(4-isopropylpiperazin-1-yl)phenoxy]-1,3-dioxolane; 1-[4-[[(2S,4S)-2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(propan-2-yl)piperazine; 1486497-66-8; UNII-6K1S7VZ5F2; SCHEMBL23346877; AOB87707; BCP31033; ZINC000006714947.
EINECS	Contact for details

Quality Control

Our 1-[4-[[(2S,4S)-2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-Ylmethyl)-1,3-Dioxolan-4-Yl]Methoxy]Phenyl]-4-Propan-2-Ylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,4S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.