Description

2-Chloro-6-(Thiophen-2-Yl)Pyrazine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines pyrazine and thiophene rings with a reactive chlorine substituent, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as semiconductors and conductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for method development and exploring new heterocyclic coupling reactions in academic and industrial labs.

Basic Information

Product Name	2-Chloro-6-(Thiophen-2-Yl)Pyrazine
CAS No.	1484099-08-2
Molecular Formula	C8H5ClN2S
Molecular Weight	196.66 g/mol
Synonyms	2-Chloro-6-(thiophen-2-yl)pyrazine; 2-(2-Chloropyrazin-6-yl)thiophene; 6-Chloro-3-(thiophen-2-yl)pyrazine; 2-Chloro-6-thiophen-2-ylpyrazine; Thiophene-2-yl-(6-chloropyrazinyl) derivative; Pyrazine, 2-chloro-6-(2-thienyl)-; 1484099-08-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Thiophen-2-Yl)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.