Description

3-Amino-1-Ethylpiperidine-2,6-Dione CAS NO 1478630-04-4 is a high-purity, specialized heterocyclic building block featuring a piperidine-2,6-dione core. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel therapeutic agents, particularly in oncology and CNS drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Linker Component: Used in the design and synthesis of bifunctional molecules for targeted protein degradation.
• Peptidomimetic Research: Serves as a constrained scaffold to mimic peptide secondary structures and enhance metabolic stability.
• Ligand Synthesis for Metal Complexes: Utilized in preparing chelating agents for catalytic or diagnostic applications.
• Agrochemical Active Ingredient Development: Employed as a building block for novel pesticides and herbicides.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-Amino-1-Ethylpiperidine-2,6-Dione
CAS No.	1478630-04-4
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	1-Ethyl-3-aminopiperidine-2,6-dione; 3-Amino-1-ethyl-2,6-piperidinedione; 3-Amino-1-ethylpiperidine-2,6-dione; 2,6-Piperidinedione, 3-amino-1-ethyl-; AE-PD; AEPD; 3-AEPD; 1-Ethyl-3-aminoglutarimide
EINECS	Contact for details

Quality Control

Our 3-Amino-1-Ethylpiperidine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.