Description

tert-Butyl 3-(2-Aminophenoxy)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative featuring both a Boc-protected amine and a primary aromatic amine, making it a versatile and valuable building block in synthetic organic chemistry. Its primary value lies in its role as a key intermediate for the synthesis of complex pharmaceutical compounds, particularly those targeting neurological and psychiatric disorders. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) active compounds and kinase inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its complex heterocyclic structure.
• Chemical Synthesis: Serves as a protected precursor for introducing the 3-(2-aminophenoxy)piperidine moiety into more complex molecular architectures.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and the exploration of new chemical entities.
• Peptidomimetics Development: Useful in creating peptide-like molecules where the piperidine scaffold mimics natural amino acid structures.

Basic Information

Product Name	tert-Butyl 3-(2-Aminophenoxy)Piperidine-1-Carboxylate
CAS No.	1464091-56-2
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1-Boc-3-(2-aminophenoxy)piperidine; tert-Butyl 3-(2-aminophenoxy)-1-piperidinecarboxylate; 3-(2-Aminophenoxy)piperidine-1-carboxylic acid tert-butyl ester; 1-Piperidinecarboxylic acid, 3-(2-aminophenoxy)-, 1,1-dimethylethyl ester; 1464091-56-2; Boc-3-(2-aminophenoxy)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-Aminophenoxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.