Description

tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine-1-carboxylate is a high-value, multi-functional piperidine derivative and a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a nitro and an ester group, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) or requiring piperidine-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the nitro and ester functionalities allow for further chemical modifications.
• Organic Synthesis Building Block: Serves as a versatile starting material for the preparation of other fine chemicals, specialty polymers, and ligands for catalysis.
• Research & Development: Essential for medicinal chemistry programs in academic and industrial laboratories for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological processes and enzyme interactions.

Basic Information

Product Name	tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine-1-carboxylate
CAS No.	1462385-41-6
Molecular Formula	C15H26N2O6
Molecular Weight	330.38 g/mol
Synonyms	1-Boc-4-(2-ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine; tert-Butyl 4-(nitromethyl)-4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate; 4-(Nitromethyl)-4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine; Boc-4-(2-Ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine; 1462385-41-6; Piperidine-1-carboxylic acid, 4-(2-ethoxy-2-oxoethyl)-4-(nitromethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with material meeting custom purity requirements, including standards suitable for pharmaceutical research (e.g., >97%, >98%, >99%).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.