Description

4-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a piperidine moiety with a benzodioxine-carbonyl group, making it a versatile precursor for the development of novel active compounds. This product is essential for research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Acts as a key scaffold or linker in the design of chemical probes and inhibitors for studying enzyme function and protein-protein interactions.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthesis in medicinal chemistry programs.
• Fine Chemical Synthesis: Utilized as a specialized intermediate for constructing complex, high-value molecules in custom synthesis and process development.

Basic Information

Product Name	4-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine hydrochloride
CAS No.	1461707-61-8
Molecular Formula	C15H19NO3·HCl
Molecular Weight	297.78 g/mol
Synonyms	4-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine hydrochloride; 4-(1,4-Benzodioxan-6-carbonyl)piperidine HCl; Piperidine, 4-[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]-, hydrochloride (1:1); 4-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carbonyl)piperidine hydrochloride; 1461707-61-8; 4-(1,4-Benzodioxane-6-carbonyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%; Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.